As part of the I All-Russian Scientific and Practical Conference with International Participation "Pharmaceutical Chemistry: Practical Implementation of Applied Science," a section was held on "Current Problems and Prospects for the Development of Pharmaceutical Microbiology: State, Challenges, Solutions, and Improvement." The session was moderated by Tatyana Chernykh, Head of the Department of Microbiology at SPHFA of the Ministry of Health of Russia, Doctor of Pharmaceutical Sciences, Professor.
Olga Gunar (Testing Center for Drug Quality Assessment) highlighted the advantages of implementing alternative microbiological methods. She presented their classification and noted that their use can significantly reduce analysis time and increase the accuracy of drug quality assessment. The speaker also emphasized the importance of harmonizing standards for the successful integration of new methods into global practice.
Olga Bogdanova, Associate Professor of the Department of Microbiology, Candidate of Biological Sciences, dedicated her report to environmental monitoring of the production area. She focused on the quality control of water for injection and analyzed the main risk factors, including the resistance of microorganisms to antimicrobial drugs. Using monitoring results as an example, the speaker justified the importance of continuous control to ensure drug safety.
Yulia Bukovskaya, a postgraduate student at the Department of Microbiology of SPHFA, spoke about the objectives of the microbiological monitoring program. The main goal is to minimize biological contamination, especially in sterile zones of classes A and B. The speaker also drew attention to the need for mandatory identification of pathogens and a systematic approach to corrective actions.
Olga Tikhomirova (SPHFA) emphasized that microbiological control is a key factor affecting consumer health. Citing statistics on drug recalls, she showed that the main threat comes from microbial contamination and violations of sanitary regimes. In conclusion, the speaker stressed the need to improve educational programs to train qualified personnel.
Alesya Moiseeva (Almazov National Medical Research Center) presented the results of a preclinical study on 30 laboratory pigs. The experiment proved that an innovative system of endotracheal tubes can delay the development of ventilator-associated pneumonia without adversely affecting the microbial landscape.
Andrey Belyankin (SPHFA, St. Petersburg Research Institute of Vaccines and Serums of FMBA) highlighted the challenges of developing multicomponent vaccines. He explained their structure using pneumococcal and meningococcal vaccines as examples and emphasized the need for strict control at all stages of production using specific analytical methods.
Experts also touched on related fields. Larisa Ilyina, Doctor of Biological Sciences, spoke about the use of molecular genetic approaches to create biological products for agriculture.
Alena Shults (SPHFA) presented approaches to creating an original broad-spectrum antimicrobial drug for veterinary practice. She noted the rise in fungal diseases in animals and the shortage of effective domestic products, emphasizing the relevance of the development. The speaker discussed the study of the drug diodiazole, during which its high therapeutic efficacy against dermatomycoses and mastitis was demonstrated, and the advantage of the developed forms (gel-creams and sprays) over existing analogues was noted.
Evgeny Brazhnik (BIOTROF LLC) presented a study on the effect of chemical stress on the biological rhythms of laying hens. The speaker showed that the introduction of glyphosate destabilizes the rhythmicity of egg laying, leading to a decrease in production performance.
The experts' reports focused on microbial safety and drug quality, decontamination, health preservation, and risk analysis at pharmaceutical and veterinary manufacturing enterprises.
A unique connection between specialists in the pharmaceutical and veterinary sectors enables them to work synergistically, guaranteeing the efficacy and safety of drug therapy.
Participants focused their attention on issues of antibiotic resistance and new approaches to the effective treatment of immunocompromised patients with combined opportunistic invasive fungal infections.
Olga Gunar (Testing Center for Drug Quality Assessment) highlighted the advantages of implementing alternative microbiological methods. She presented their classification and noted that their use can significantly reduce analysis time and increase the accuracy of drug quality assessment. The speaker also emphasized the importance of harmonizing standards for the successful integration of new methods into global practice.
Olga Bogdanova, Associate Professor of the Department of Microbiology, Candidate of Biological Sciences, dedicated her report to environmental monitoring of the production area. She focused on the quality control of water for injection and analyzed the main risk factors, including the resistance of microorganisms to antimicrobial drugs. Using monitoring results as an example, the speaker justified the importance of continuous control to ensure drug safety.
Yulia Bukovskaya, a postgraduate student at the Department of Microbiology of SPHFA, spoke about the objectives of the microbiological monitoring program. The main goal is to minimize biological contamination, especially in sterile zones of classes A and B. The speaker also drew attention to the need for mandatory identification of pathogens and a systematic approach to corrective actions.
Olga Tikhomirova (SPHFA) emphasized that microbiological control is a key factor affecting consumer health. Citing statistics on drug recalls, she showed that the main threat comes from microbial contamination and violations of sanitary regimes. In conclusion, the speaker stressed the need to improve educational programs to train qualified personnel.
Alesya Moiseeva (Almazov National Medical Research Center) presented the results of a preclinical study on 30 laboratory pigs. The experiment proved that an innovative system of endotracheal tubes can delay the development of ventilator-associated pneumonia without adversely affecting the microbial landscape.
Andrey Belyankin (SPHFA, St. Petersburg Research Institute of Vaccines and Serums of FMBA) highlighted the challenges of developing multicomponent vaccines. He explained their structure using pneumococcal and meningococcal vaccines as examples and emphasized the need for strict control at all stages of production using specific analytical methods.
Experts also touched on related fields. Larisa Ilyina, Doctor of Biological Sciences, spoke about the use of molecular genetic approaches to create biological products for agriculture.
Alena Shults (SPHFA) presented approaches to creating an original broad-spectrum antimicrobial drug for veterinary practice. She noted the rise in fungal diseases in animals and the shortage of effective domestic products, emphasizing the relevance of the development. The speaker discussed the study of the drug diodiazole, during which its high therapeutic efficacy against dermatomycoses and mastitis was demonstrated, and the advantage of the developed forms (gel-creams and sprays) over existing analogues was noted.
Evgeny Brazhnik (BIOTROF LLC) presented a study on the effect of chemical stress on the biological rhythms of laying hens. The speaker showed that the introduction of glyphosate destabilizes the rhythmicity of egg laying, leading to a decrease in production performance.
The experts' reports focused on microbial safety and drug quality, decontamination, health preservation, and risk analysis at pharmaceutical and veterinary manufacturing enterprises.
A unique connection between specialists in the pharmaceutical and veterinary sectors enables them to work synergistically, guaranteeing the efficacy and safety of drug therapy.
Participants focused their attention on issues of antibiotic resistance and new approaches to the effective treatment of immunocompromised patients with combined opportunistic invasive fungal infections.